Kaletra: indications, composition, side effects
Kaletra is an innovative drug manufactured by Abbott laboratories, a British company. The drug is an antiviral substance that has a serious impact on HIV infection. Doctors prescribe this drug for the treatment of detected HIV infection.
Under the influence of active compounds of this drug, the replication of the virus, which provokes immunodeficiency in humans, is inhibited. Before using the drug, it is important to know exactly the dosage of the drug and its composition.
Indications for use
The instructions for use attached to the drug Kaletra allow you to learn about the indications for use of this drug. You can also find out about them in the reviews. The main indication is the treatment of HIV infection. Generic Kaletra can be used to inhibit the development of HIV infection in adults, as well as in young patients from 3 years old.
Application and dosage
Generic Kaletra tablets are taken orally. They are swallowed whole, and it is not recommended to chew them or break them. You can take the drug without focusing on the time of the meal. The recommended dosage for adult patients is 400/100 mg twice a day or 800/200 mg once a day. In this dosage, the drug can only be taken by patients who have not previously received antiretroviral therapy.
For those patients who have previously undergone such treatment, the dosage of the drug is 400 mg/100 mg. Generic Kaletra in this amount is taken twice during the day. Specialists do not prescribe such a dose once per day.
If the patient has decreased sensitivity to lopinavir, which has been confirmed by laboratory and clinically, in this case, the dose should be increased to 500/125 mg. the Patient should take two pieces 200/50 mg and one 100/25 mg or during the day to take 5 pieces of 100/25 mg to combine the asset with nevirapine, with efavirenz.
Children who have a weight of 35 kilograms and a body surface area of more than 1.4 square meters are recommended to prescribe the drug in a dosage of 400/100 mg. the Drug is taken twice during the day, and the use of additional therapeutic agents-nevirapine and efavirenz should be excluded. For small patients who have a weight of less than 35 kg and a body surface area of less than 0.6 square meters, the dose of the drug is calculated individually according to a special scheme. Patients of small age who have a body surface area of less than 0.6 square meters are recommended to use Claveter solution.
The drug in the form of a solution is taken orally during meals. For adult patients, the dosage is 5 ml. during the day, the therapeutic composition is taken twice. For patients who have not previously taken antiretroviral drugs, the dosage is 10 ml once per day.
For children who weigh more than 40 kilograms, the daily dosage should not be more than 5 ml of the solution. This amount of the drug the patient should take 2 times during the day. When the main drug is used simultaneously with ranitidine and omeprazole, dose adjustment is not required. When conducting combination therapy in adult patients using drugs such as nevirapine and efavirenz, you can not prescribe generic Kaletra once a day. And for a dose of 400/100 mg, which is taken twice a day, no adjustment is required.
Early clinical studies have shown that there is no need to make adjustments to the dose prescribed by the doctor during pregnancy. Pregnant women are contraindicated to use lopinavir and ritonavir in a dosage of 1 time per day. This is due to the fact that there is little clinical and pharmacokinetic data on the effect of these substances on the body of women in an "interesting position".
- severe liver disease;
- simultaneous use of several drugs that affect the heart, such as statins, ergot alkaloids;
- treatment of newborns in the first six months of life;
- lactation. If the drug Kaletra is prescribed for the treatment of HIV infection, breast-feeding of the child is stopped for the period of treatment;
- pregnancy. But sometimes when carrying a fetus, this medication is prescribed. However, this is extremely rare.
Kaletra, like any drug, has certain contraindications. From the instructions for use, you can learn about the main restrictions for using this tool. These include the following:
You can learn about the side effects that may occur in the patient when using this drug from the instructions or reviews on the Internet. Patients experience the following unpleasant symptoms during treatment:
- diarrhea, nausea, vomiting. Their appearance may occur at the beginning of therapy or these symptoms may occur later;
- migraine, decreased sleep quality;
- arterial hypertension. In rare cases, atherosclerosis and myocardial infarction occur;
- appearance of a rash on the skin, dermatitis, eczema.
HIV infection is a pathology that is difficult to treat. The pharmaceutical industry is constantly working to create new tools that can be used to effectively treat this disease. Today, in the pharmacy network, you can find several drugs that, when used, help to inhibit the development of HIV infection. One of them is Kaletra.
The use of this drug can reduce painful symptoms and slow down the development of the disease. The drug can be used both for the treatment of adults and for the treatment of young patients. The dosage varies depending on the age group of patients. When prescribing a dose of medication, the patient's condition is taken into account.
Before starting therapy, you should find out the contraindications and side effects, so that there is no harm to health in the fight against HIV infection. The use of this drug provides a high effect. This is indicated by reviews that can be found on the Internet. Many patients in their reviews call this tool effective. Also, former patients indicate that this drug has many side effects. Combining this drug with alcohol is not recommended, so as not to reduce the therapeutic effect of taking the drug.
The first weeks of using the drug, if you believe the reviews, the patient experiences unpleasant sensations. Many people in the reviews indicate that they suffered from diarrhea during treatment with this drug, while noting that the condition gradually improves, the effect of the drug increases, which contributes to the normalization of indicators.
It is not always possible to find this remedy in a pharmacy. In the absence of the drug, analogues of Kaletra come to the aid. They can be found at a pharmacy or ordered online. Note that the contraindication to the use of this medication is pregnancy. For this reason, women in an "interesting position" are not prescribed treatment with this drug. Lactation is another contraindication. When prescribing Kaletra, breastfeeding is suspended for the duration of taking the drug.
Kaletra is an effective drug that is recommended by many patients. Doctors also speak positively about this medicine. Although the drug is quite expensive, but when it is used, people infected with HIV can improve their condition and slow down the development of the disease.